Bone Cement – Science Behind
Fixation of bone needs to be stable for a long period of time. This can be accomplished by using a biological or cement–based.
- Biological anchorage – involves stimulating bone growth inwardly by improving tissue contact with the biological surface.
- Cement anchorage – involves filling of bone gaps between implant and the bone of the body.
Self-curing cement was used in the early days and now PMMA ( Polymethylmethacrylate) is commonly used in bone cement and the monomer form, MMA is employed in dental and oral surgeries. Total Hip replacement surgeries, Total hip replacement surgeries use bone cement majorly.
Composition
The powder component of the bone cement contains a polymer that is polymethylmethacrylate, initiator such as benzoyl peroxide brings about radiodensity and an antibiotic in case of antibiotic-loaded cement. The liquid component contains monomer MMA and a DMPT as an accelerator. The antibiotic component in the bone cement helps to clear out bacterial infections in the body. Bone cement can be considered a drug delivery system as it delivers the antibiotic to the body.
Phases of Bone Cement
Dough Time
From the beginning of the mixing to the stage where the cement doesn’t stick to the hands is called the dough time. This happens after 2-3 minutes typical for most PMMA cements.
Working Time
This is the end of dough time until the cement becomes too hard to manipulate, typically lasts for about 5-8 minutes.
Setting Time
From the mixing to the stage of heat release is called the setting time , 8-10 minutes.
Subiton Bone Cement
Subiton , from Laboratorios SL S.A , produce bone cement of different variants. Subiton RO, Subiton G , Subiton GUN, Subiton GUN G are few of the bone cements from Subiton . Morulaa Healthtech Pvt Ltd. is the licensed importer of Subiton. 
Subiton, also known as Laboratorios SL, is an Argentine firm that has been a world leader in medical devices since 1957. These products are manufactured in environment-conscious facilities, serves over 110 nations. It has obtained certification of its products in India. In India, distributors usually provide bone cement along with orthopedic implants to hospitals. The players in the supply chain include the manufacturer, importer, distributor or dealers, etc.
Factors that affect bone cement preparation
- Ambient Temperature – higher temperature, shorter phases, and lower temperature, longer phases
- Mixing process – if mixing is done quickly or aggressively, polymerization reaction occurs faster and the cement sets quick.
- Kind of Cement – different types of cement have different setting times.
The powder to liquid ratio also plays an important role in the bone cement preparation.
Fields of Use
- Orthopedics
- Knee
- Hip
- Shoulders
- Spine
- Traumatology
- Neurosurgery
- Dental
Other indications include, Rheumatoid arthritis, necrosis, sickle cell anemia, revision surgeries, and other arthroplasty procedures.
Conclusion:
The above article deals with bone cement, the science, principle and advantages. Subiton products are of high-quality, provided at a competitive price. Morulaa’s imported cement is well suited to give stability to implants used in total knee replacement and total hip replacement surgeries.
This article is intended to give product information on Subiton bone cement. To know more about the product details, brochure please visit products.morulaa.com.
Morulaa is a turnkey solution provider with an in-house Regulatory Consultancy team to conduct registrations of medical devices. Morulaa provides high-quality and professional services for Regulatory Consultancy and we aim at developing long-term relationships for the Indian Market.
