The gastroduodenal Full-Thickness Resection Device (FTRD®) is a specialized system designed for deep partial-wall and full-thickness resections in the stomach and duodenum. It is particularly useful for handling lesions that do not lift, such as non-lifting adenomas, small subepithelial tumors, and early carcinomas. This device is designed for safer insertion into the upper gastrointestinal tract with features like an insertion balloon and a guide wire. The gastroduodenal FTRD® set includes a modified clip to suit the specific anatomical requirements of the stomach and duodenum. It provides a minimally invasive option for both diagnostic tissue acquisition and therapeutic interventions.