The FTRD® Set, or Full-Thickness Resection Device, is a specialized tool used in flexible endoscopy for the removal and diagnostic analysis of lesions across various layers of organ walls, including the serosa. It operates on the principle of the OTSC® System, ensuring that organ walls are transected only after the targeted site is securely closed, thereby maintaining the integrity of the organ lumen during procedures. The device is particularly effective for endoscopic full-thickness resection (EFTR) and diagnostic tissue acquisition in the colon, rectum, stomach, and duodenum. The set includes a preloaded clip, an integrated snare, and additional tools to enhance safety and efficacy in tissue resection and retrieval.